The nerve-conduction test is only sensitive to damage in the large-fiber nerves. In contrast, patients with small-fiber neuropathy may have symptoms of pain, burning, and prickling, even without weakness. Symptoms of large-fiber neuropathy include weakness and poorly localizable numbness, and are associated with abnormalities on nerve-conduction tests. Neuropathy can target nerves either of larger or smaller caliber, respectively referred to as a “large-fiber” neuropathy and a “small-fiber” neuropathy. Sjögren’s syndrome may uniquely target nerves which are not tested on normal nerve-conduction tests. Why is Neuropathy Under-Diagnosed or Under-Treated in Sjögren’s Syndrome?ġ. If the neurological examination confirms a peripheral neuropathy, then you may have a nerve-conduction test, looking at the integrity of nerves and muscles. Your physician may also test your ability to appreciate temperature, a sharp pin, and vibration.

However, patients with neuropathy may not have any reflexes. Typically, a reflex hammer should elicit emphatic lurches of arms and legs. Weakness may be present, which is typically greater in the toes and fingers than in the larger muscle groups of the arms and legs. A neurological examination is crucial in providing objective evidence of peripheral neuropathy. The pattern and description of symptoms, which may include pain and weakness, could suggest damage to the peripheral nerves.

The first step is to take a careful history and perform a physical examination. Neuropathy can cause various symptoms, from “numbness,” to “coldness” in its most severe, neuropathy has been described as “burning”, “lancinating”, or “feeling like my skin is on fire.” Neuropathy can also cause weakness and clumsiness. Neuropathy, which means inflammation and/or damage to the peripheral nerves, can be affect patients with Sjögren’s syndrome. Peripheral Neuropathy of Sjögren’s Syndrome Sjögren’s syndrome can cause inflammation and damage to both the CNS and PNS. The “ Peripheral Nervous System” – or PNS – includes larger and smaller nerves, connecting muscles to the spinal cord.The “ Central Nervous System” – or CNS – includes the brain and the spinal cord.

The nervous system is divided into two anatomic compartments: The neurological complications of Sjögren’s syndrome are extensive and range from cognitive difficulties, to burning toes and feet. Johns Hopkins Neurology-Rheumatology Clinic A PRIMER ON THE NEUROLOGICAL COMPLICATIONS OF SJÖGREN’S SYNDROME

Do nerve conduction tests hurt